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The risk of type 2 diabetes (T2D) is related to lifestyle but less is known about how lifestyle factors interact and how they impact the risk when combined. This study was performed to analyze how lifestyle factors relate to the cumulative incidence of T2D in a Swedish rural population. Outcomes were generated from national registers and from two surveys. Two hundred sixty men (11%) with diabetes were found in the registers, and 193 men with T2D were identified in the surveyed population (9.8%). Physical activity (OR for high physical activity=0.55 (95% CI 0.31-0.97) and meal quality (OR for high meal quality=0.58 [95% CI 0.350.99] were significantly related to T2D in the adjusted analyses. Other lifestyle factors had no significant relationship with T2D in this study. An interaction between physical activity and meal quality was revealed, indicating that a healthy lifestyle in one of the aspects does not compensate for an unhealthy choice in the other.

Type 2 Diabetes and Lifestyle- A Prospective Population-Based Cohort Study among Rural Men