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Development of disease in humans is increasingly diverse and runs quickly. One cause of the incidence of various diseases are microorganisms such as Escherichia coli. The usual treatment is the use of chemical drugs, which can cause the effects of resistance to bacteria and even side effects for patients, so it is important to do business utilization of plants as herbal medicinal materials by utilizing the waste of sweet orange seeds as an antibacterial. This study aims to determine the antibacterial activity of orange seeds (Citrus sinensis) against Escherichia coli. This study is designed as an laboratory experimental with diffusion method for the antibactey test. The study was conducted with the following stages: (1) preparation of the sample of orange seed powder, (2) maseration of orange seeds powder with n-hexane and ethanol solvent, (3) antibacterial test. The results showed that orange seeds inhibited the growth of Escherichia coli with inhibition zone of n-hexane and ethanol extracts of 7.93±1.90 mm and 18.27±2.40 mm. Sweet orange seeds (Citrus sinensis) have the potential as antibacterial.

AKTIVITAS ANTIBAKTERI BIJI JERUK MANIS (Citrus sinensis) TERHADAP BAKTERI Eschericia coli