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Pyoderma gangrenosum, acne and suppurative hidradenitis (PASH) syndrome (1) is described as an autoinflammatory disorder, similar to pyogenic sterile arthritis, pyoderma gangrenosum and acne (PAPA) syndrome, but without joint involvement, thereby satisfying the criteria of a disease entity distinct from infection, allergy and autoimmune disorders (2). A specific genetic mutation underlying PASH syndrome has not yet been identified. Treatment strategies for PASH syndrome and their efficacy have not been well documented. We report here a case of PASH syndrome that was successfully treated with granulocyte and monocyte adsorption apheresis (GMA) therapy, followed by adalimumab.

Pyoderma Gangrenosum, Acne and Suppurative Hidradenitis Syndrome Treated with Granulocyte and Monocyte Adsorption Apheresis