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Mycetoma is a chronic, subcutaneous infection caused by traumatic inoculation through the skin of some types of filamentous aerobic bacteria (actinomycetoma) and true fungi (eumycetoma) (1, 2). It is considered a neglected disease with high morbidity and major effects on the patient’s quality of life (1–3). Few published cases have examined mycetoma during pregnancy (4–7). We report here a case of a patient with eumycetoma on her foot that exhibited significant clinical worsening during pregnancy, which illustrates the difficulty of treatment of this infection during pregnancy, when consideration of the teratogenic and toxic effects of antifungal drugs is paramount.

Eumycetoma on the Foot Caused by Madurella mycetomatis: Amputation After Significant Worsening During Pregnancy