English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

We previously reported that 10 nights of moderate hypoxia (∼15% O2; 10 h per night) improved glucose homeostasis (glucose disposal rate [GDR] during a hyperinsulinemic-euglycemic clamp) in obese men (1). Goossens (2) now raises some important questions about our study and puts forward an intriguing alternate hypothesis to explain our results that nightly hypoxia treatment improves whole-body insulin sensitivity.First, Goossens points out that the improvement in GDR may be explained by a reduction in food intake and concomitant weight loss. Indeed, altitude-associated hypoxia has been shown to trigger significant reductions in energy intake (3). Although we did not collect information on food intake, study participants were instructed to follow …

Response to Comment on Lecoultre et al. Ten Nights of Moderate Hypoxia Improves Insulin Sensitivity in Obese Humans. Diabetes Care 2013;36:e197–e198