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We thank Professor Home for his interest (1) in our publication on a novel basal insulin analog, LY2605541 (2).Total, LDL, and HDL cholesterol levels along with triglyceride levels (or lipid profiles) were measured as noted in the last paragraph on page 2144 (2). Whereas the serum triglyceride measurements for the LY2605541-treated patients did not differ from baseline but were higher compared with insulin glargine–treated patients, the total, HDL, and LDL cholesterol did not differ from baseline for the LY2605541-treated patients and did not differ from those treated with insulin glargine. In contrast, in the recently published type 1 diabetes study (3), LY2605541-treated patients …

diabetes care

Response to Comment on: Bergenstal et al. A Randomized, Controlled Study of Once-Daily LY2605541, a Novel Long-Acting Basal Insulin, Versus Insulin Glargine in Basal Insulin-Treated Patients With Type 2 Diabetes. Diabetes Care 2012;35:2140-2147