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L-carnosine was discovered by Gulewitsch in 1900 and its granulation effect was confirmed by Nagai and his associates in 1970. This chemical works beneficially on the inflammatory tissues by way of promoting their healing process quickly. After healing, L-carnosine will remain free of further effect. In the present study, the authors applied L-carnosine in a spray form to the cases of gingivectomy and apicoectomy to prove the Nagai's theory in a clinical environment, without use of either analgesic or antiinflammatory drugs.As a result, inflammations were completely checked by promoting the healing process alone. The present findings are in confirmation of his theory and is interpreted as one means of inhibiting an inflammation through the promotion of spontaneous healing.

Heilende Wirkung von L-Carnosin auf Operationswunde bei Apikoektomie und Gingivektomie