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1.1 Healing of the wound Healing of the wound, which is a primary concern in surgery, is currently effected by three measures of the hemostasis, prevention of an infection and antiphlogistic measure, so that conditions most favorable to a natural heal may result in. However, it is far from directly influencing the mechanism that restores a pathological physiologic state. When something happens which interferes with this natural healing process, any clinical attempt at its cure will become correspondingly difficult. These cases may include the opening of postoperative wounds, keloidosis, decubital ulceration, alveolar pyorrhea and dry socket complaints in the dental domain. In recent years, in addition, interferences with the natural healing are recognized to come from an excessive administration of such drugs as tend to inhibit the vital defense reaction, including carcinostats, antiinflammatory drugs, steroid preparations and antiimmunologic agents. A change in our philosophy of the healing process of a vital body is bound to come about, if we want to deviate from the current practice of having recourse to a healing of wound merely from a biochemical point of view. Since the healing of wound is terminal to an inflammatory reaction, a major portion of the previous investigations has been addressed to this negative component of an inflammation, i.e., interference or inhibition of the manifestation of an inflammatory reaction. It is for this very reason that many steroid and non-steroid preparations which are screened in terms of inhibiting the granular process due to an inflammation

A Curative Effect of Carnosine (β-alanyl-1-histidine) on the Decubital Ulcer