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The flow rate of human erythrocytes on microchannels was measured to evaluate their deformability when treated with soy phospholipids, hydrogenated soy phospholipids, phospholipids containing icosape-ntaenoic acid (EPA) and docosahexaenoic acid (DHA). EPA-containing phosphatidylserine and DHA-containing phosphatidylcholine or phosphatidylethanolamine were observed to be the most effective lipid molecular species to improve the deformability of human erythrocytes, while hydrogenated phospho-lipids tended to impair deformability

Effect of in vitro Treatment with Glycerophospholipid Containing Highly Polyunsaturated Fatty Acids on Deformability of Human Erythrocytes.