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Comparative studies of halothane-02 (OF), enflurane-02 (OE), halothane-02-N20 (GOF) and enflurane-02-N20 (GOE) anesthesia on a number of clinically important features were made in the cat. Cats of each group were premedicated with atropine (0.05 mg/kg) subcutaneously and ketamine (5 mg/kg) intramuscularly. Anesthesia was induced (via face mask) and maintained for 60 minutes at surgical depth with halothane and enflurane in either 02 or a combination of 02 and N20 (1 : 2) via a semiclosed circle system under a spontaneous ventilation. Mean alveolar concentrations of halothane and enflurane during maintenance anesthesia were 1.93% in OF group, 2.56% in OE group, 1.29% in GOF group and 1.81% in GOE group. Anesthetic induction was more rapid in GOF and GOE groups than in OF and OE groups. Recovery was significantly rapid in OE group compared with OF group. Respiration rates during anesthesia were significantly lower in OE and GOE groups than in OF and GOF groups, however, the changes in arterial pH and PCO2 showed a nearly equal degree of respiratory acidosis in all groups. Abnormal electrocardiographic alterations were not observed in cats of all groups. Arterial blood pressure was significantly higher in GOF and GOE groups than in OF and OE groups, and was slightly higher in OF and GOF groups than in OE and GOE groups. Changes in serum GOT and BUN were within normal ranges in all cats examined. These results suggest that a use of N2O is preferable in halothane and enflurane in the cat and that there are no significant differences between the two for the clinical application in cats.

Comparative studies of halothane (OF and GOF) and enflurane (OE and GOE) inhalation anesthesia in cats.