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Copper inhibited the photoreduction of DCPIP (PS II activity) in a spheroplast preparation of cyanophage AS-1-resistant mutant (An/AS-1). The inhibitory action of Cu2+ was reversed by supplementation with manganese but not with DPC. The results suggest that the site of inhibition was either between the Mn2+ and DPC donation site(s) or close to DPC donation site. Protection of the Hill activity by EDTA further suggestes that Cu2+ interacted with the reaction center.

Copper inhibition of photosystem II activity in the cyanophage As-1-resistant mutant.