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The analysis of biospecimens from astronauts reveals considerable important information about their healthcare, but transportation of such samples will become difficult after the retirement of the Space Shuttles. We focused on hair, which is one of the easiest specimens to obtain, store and return, and planned this "Biomedical Analysis of Human Hair Exposed to Long-term Space Flight (Hair)" study. The main objective of the present part is to verify whether changes in mineral metabolism can be detected through analysis of hair shafts from astronauts on the International Space Station. Ground-based studies were performed to establish an optimum methodology for analyzing trace elements (e.g., calcium, sulfur and chlorine) on the cross-sectional surface of a hair shaft. By using Electron Prove Micro Analyzer (EPMA), we could identify the distribution of minerals in human scalp hairs. In another animal study, a centrally distributed concentration of calcium was observed in hairs from the mice exposed to microgravity. In this paper, we will report on the overall research plan and the progress we have made to date.

transactions of the japan society for aeronautical and space sciences, aerospace technology japan

Preliminary Studies for ^|^ldquo;Biomedical Analysis of Human Hair Exposed to Long-term Space Flight (Hair)^|^rdquo; Project: An Analysis of Trace Elements in the Hair