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This study establishes a toxicity assessment of the mixture of Fe3+, Mn2+, and Al3+ ions by employing a Probit dose-response model and an augmented simplex design. The toxicity of individual Fe3+, Mn2+, and Al3+ metal ions with respect to Escherichia coli DH5i is in the order of Mn2+ > Fe3+ > Al3+. The mixture of Fe3+, Mn2+, and Al3+ ions shows a hump region and a saddle region in the IC50 values contour plot. Fe-Mn-Al ternary alloys may possess a lower toxic risk when the ratio of released metal ions approaches the hump region of the contour plot. FeMn-Al ternary alloys may present an increased toxic risk when the ratio of released metal ions gets close to the saddle regions of the contour plot. [doi:10.2320/matertrans.M2014108]

Toxicity Assessment of Fe-Mn-Al Ternary Alloys Using a Probit Dose-Response Model and an Augmented Simplex Design