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Ti29Nb13Ta4.6Zr (TNTZ) which was developed for biomedical applications, is a btype titanium alloy with a relatively low Young's modulus. However, its fabrication cost is high because the alloying elements of Nb and Ta, which are bstabilizers with high melting points, are expensive and rare metals. In this study, TiMn system alloys were developed as lowcost titanium binary alloys for biomedical applications, and their mechanical properties (tensile strength and Young's modulus) and biocompatibility (bone contact ratio) were investigated to evaluate their possible use as next generation metallic biomaterials. Ti12Mn has a tensile strength of approximately 950 MPa, which is similar to those of annealed Ti6Al4V ELI (Extra Low interstitial) and insufficiently aged TNTZ. Ti9.2Mn has the lowest Young's modulus of approximately 90 GPa among the alloys investigated. The mean values of bone contact ratios on Ti12Mn were obtained 12, 52 and 96 weeks after the implantation of rabbit femurs and were found to be slightly lower than the values for commercially pure Ti, although a small amount of Mn element was detected at a interfacial bone tissue with the concentration gradient at 96 weeks after implantation. However, there appeared to be no significant effects of the release of Mn to the bone tissue on bone formation. From these results, it is considered that TiMn system alloys are promising biomaterials with attractive mechanical properties and relatively good biocompatibility. [doi:10.2320/jinstmet.J2013003]

Mechanical Properties and Biocompatibility of Low Cost-Type Ti-Mn System Binary Alloys for Biomedical Applications