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To (1) document the prevalence and patterns of hypodontia (permanent tooth agenesis) in Down syndrome (DS) and (2) explore whether maxillary or mandibular hypodontia or simultaneous agenesis of all third molars was associated with differential alterations of the craniofacial morphology.

Prevalence and patterns of permanent tooth agenesis in Down syndrome and their association with craniofacial morphology