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Water transport in cells and tissues is essential for life. When water molecules move into or out of the cell or from one subcellular compartment to another they have to cross the cell membranes, which form the barrier between the interior and exterior of cell or between cell organelles and cytosol. I have edited a two volume book1 providing in depth presentations of water transport in a variety of biological membranes. Since the membrane proteins confer to biological membranes a much higher water permeability compared to the lipid counterpart, by water channels we understand in fact the water channel proteins, those transmembrane proteins that have as their main (specific) function the transport of water. In 1993 the water channel proteins were called aquaporins.

keio journal of medicine

Water channel proteins: from their discovery in Cluj-Napoca, Romania in 1985, to the 2003 Nobel Prize in chemistry and their implications in molecular medicine