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We have newly established a human megakaryoblastic cell line (MKB-01) from acute megakaryoblastic leukemia. In this study, we have focused on cell kinetics of megakaryoblastic progenitors during the establishment of the megakaryoblastic cell line. Original blasts were obtained from the bone marrow of a 61-year-old man with acute megakaryoblastic leukemia. The bone marrow contained 75% blasts which were identified as megakaryoblasts by positive platelet peroxidase (PPO) activity and platelet

A cell kinetic study of megakaryoblastic progenitors during establishing megakaryoblastic cell line.