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Using duplex carotid ultrasonography, we measured the mean flow velocity in common carotid artery and examined the atherosclerotic lesions (plaque) in 30 patients with lacunar infarction (L group) and 99 patients without cerebral infarction (C group) . L group was diagnosed on clinical symptomatology and infarction size (≤15 mm) by brain CT or MRI. The mean flow velocity (25.3±4.7cm/s) in the L group was significantly lower than that (31.1±7.4cm/s) in the C group. The difference of the mean flow velocities between the L and C groups was considered to be based on the difference of peripheral resistance. In the L group, the mean flow velocity on the affected side was not significantly different from that on unaffected side. Incidence of atherosclerotic lesions (plaque) in the L group was significantly higher than that in the C group.These results suggested that the cerebral atherosclerosis was more advanced in patients with lacunar infarction than in those without brain infarction.

Evaluation of lacunar infarction by duplex carotid ultrasonography.