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The correlation between continuity of cerebral blood flow velocity (CBFV) pattern (internal carotid artery) and cerebral vascular resistance, indicating cerebral arteriosclerosis (CA), was investigated by the ultrasonic Doppler technique. A significant correlation between continuity of the CBFV pattern and the severity of CA was recognized: the greater the decrease in continuity of the CBFV pattern, the greater the severity of CA. In a previous study, the continuous index (CI) of the CBFV pattern was devised as an objective parameter of the continuity of the CBFV pattern for evaluating cerebral hemodynamics in CA. Pulsatility index (PI) and resistance index (RI) are similar in nature to the CI. These parameters are useful as objective indexes of cerebral vascular resistance, indicating CA, particularly of the arteriole. Among these parameters, PI seems to be more useful clinically than CI and RI. Criteria for the quantitative detection of CA, particularly of the arteriole, are proposed by calculation of the PI.

Quantitative Detection of Cerebral Arteriosclerosis by the Ultrasonic Doppler Technique: Criteria for the Diagnosis of Cerebral Arteriosclerosis.