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/Objective. The proportion of live-born infants conceived with  assisted reproductive technologies (ART) in some European countries reaches  6% and in Serbia over 1%. The aim of this study was to analyze  characteristics and morbidity of prematurely born newborns conceived with  ART. Methods. The study included 154 prematurely born newborns from  pregnancies conceived with ART and 154 prematurely born newborns conceived  naturally hospitalized at the Institute of Health Care of Children and  Adolescents of Vojvodina. Participants from both groups were matched  according to gestational age and date of birth. Results. Statistically  significantly more newborns with very low birth weight have been in group of  newborns conceived by ART in comparison to newborns conceived naturally (χ2  test, p = 0.0002). Morbidity of newborns conceived with ART is not higher in  comparison to newborns of the same gestational age conceived naturally.  Bronchopulmonary dysplasia, occurred more frequently in children from ART (χ2  test, p = 0.006) and retinopathy of prematurity, occurred more frequently in  children spontaneously conceived. (χ2 test, p = 0.047). There was no  difference in the frequency of birth defects, genetic syndromes and inborn  errors of metabolism between two groups. Conclusion. Lower birth weight and  intrauterine growth restriction are potential risk factors for worse  postnatal outcome in newborns from pregnancies conceived with ART.

Characteristics and morbidity of prematurely born newborns conceived with assisted reproductive technologies