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. Athersclerosis is a multifactorial disease that begins in  childhood. There are few reports regarding influence of risk factors on the  atherosclerotic processes in early period of life and adolescence. Objective.  The aim of this study was to present and analyze risk factor trends in school  children over a 10-year period that were included and followed-up by the  Yugoslav Study of Atherosclerosis Precursors in School Children (YUSAD  Study). Methods. There were three examinations of selected population from 13  centres. The first examination was performed when children were 10 years of  age (first group; N=6381 participants), the second examination on the same  population when they were 15 years of age (second group; N=5017) and third  when children were 19/20 years of age (third group; N=1293). Evaluated  parameters included: BMI, waist circumference (WaC) and lipid profile (total  cholesterol, HDL cholesterol, LDL cholesterol and triglyceride). Results. A  significant elevation of values (p<0.001) of BMI, WaC and triglycerides and a  significant decline (p<0.001) of total cholesterol and LDL cholesterol in  boys over 5 and 10-year period was noticed. There was a significant elevation  (p<0.001) of BMI, WaC and HDL values and a significant decline in LDL  cholesterol values in girls over the 5 and 10-year period. Conclusion. Our  results point out that girls between 10 and 19/20 years have a better lipid  profile during growth. It should be stressed out that childhood and  adolescence can be more beneficial in the observation of risk factor  influences on pathological, genetic and clinical levels

Anthropometric and lipid parameters trends in school children: One decade of YUSAD study