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Fast, easy, and scalable methodologies for the synthesis of  unsymmetrically-substituted secondary amines containing naphthalene, indole,  pyridine and imidazole moieties through reductive amination were explored.  The investigated operating procedures were successful on a 50- to 30-mmole  scale, and presented a high potential for upscaling

Scalable methodologies for the synthesis of novel unsymmetrically-substituted secondary amines