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One of the new promising candidate genes defining productive qualities of   sheep is MEF2B. Protein from the MEF2 group encoded by it affects the   production of myostatin and the expression of the genes responsible for the   growth of skeletal muscle fibers. Thus, the knowledge of the MEF2B gene   structure is important for genomic selection. We have studied the structure   of the MEF2B gene at sheep of Severokavkazskaya breed bred in Russia. To   detect alleles we use NimbleGen sequencing technology by Roche (USA). As a   result, it was revealed 14 single nucleotide polymorphisms (SNP) at the   given breed. The discovered SNPare located in not coding areas. From them 7   polymorphisms are in the area of 5’ upstream gene in loci: c.-1713, c.-1319,   c.-839, c.-321, c.-246, c.-161, c.-3; 6 polymorphisms are in introns, loci:   c.55-51, c.258+312, c.258+380, c.259-52, c.452+95, c.452+103, 1 SNP is in 3’   downstream gene, c

MEF2B gene SNP markers of meat productivity in Severokavkazskaya sheep breed