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The kinetic models are fundamental knowledge of biochemical and microbial processes. The aim of the work is the kinetic model research based on biochemical and microbial mechanisms of the cell growth, the substrate consumption and the product formation. The engineering goal is to obtain ethanol as a fuel from renewable resources by a biosynthesis process. The engineering goal requires the inclusion of the inhibitory effect of a high substrate and ethanol concentration in the kinetic models. The interactions of the ethanol synthesis with the growth biomass mechanism were researched. The models of the ethanol forming mechanisms were incorporated in the complex structure of the kinetic models. The researches of the kinetic models were realized by computer simulation and experimental verification at the ethanol biosynthesis process from glucose with free and immobilized cells Saccharomyces cerevisiae. The model parameters and the limits were estimated by experimental validation. The base of the verified deterministic and semi-empiric kinetic models was created. The model base may be onward used for the process simulation models generating.

The kinetic models of the bioprocess with free and immobilized cells