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Candida spp. form a part of human and animal oral cavity flora. However   Candida spp. is the main cause of dental related stomatitis in humans and   stomatitis in dogs. Stomatitis treatment implies the use of azoles and   polyenes to which yeasts build up resistance. The research is directed to the   use of natural compounds such as essential oils. The aim of this paper is to   define the antifungal activity of thyme oil on 15 clinical strains of Candida   spp., isolated from humans and dogs and to determine if there is a difference   in susceptibility between human and dog isolates. Sampling in patients with   stomatitis was done by swabbing the denture or oral mucosa swab while   sampling in dogs was done by swabbing the oral cavity mucosa after stomatitis   has been diagnosed. In order to investigate the antifungal activity of thyme   oil in vitro, microdilution method was used. Thyme oil expressed antifungal   effects on all investigated strains. Also, our data show that the values of   minimum fungicide concentration (MFC) and minimum inhibitory concentration   (MIC) are lower in human strains. Explanation is that in most cases,   stomatitis in humans is asymptomatic and thus not treated, so Candida strains   have not developed resistance. On the other hand, stomatitis in dogs is   followed by a marked clinical picture and treated is by antimicotics (mostly   by azoles), therefore resistant Candida strains are more likely to occur

Susceptibility profile of Candida spp. isolated from humans and dogs with stomatitis to the essential oil of Thymus vulgaris