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We describe the periodic dilution rate and periodic mortality of a stochastic chemostat model with the response of the Monond function. We consider that both nutrient’s input concentration and the death rate of microbe are simultaneously influenced by white noise. For this chemostat, we have found sufficient conditions which have a stationary distribution and stochastic nontrivial positive periodic solution.

Stationary Distribution and Periodic Solution for the Stochastic Chemostat with Perturbations on Multiple Parameters