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espanolPresentamos un caso de una paciente de mediana edad con ingesta mantenida de anticonceptivos hormonales (AH) que desarrolla multiples adenomas hepaticos (asociacion bien documentada) y un carcinoma hepatocelular (CHC) unifocal gigante, sin encontrar otros factores de riesgo para el mismo (enolismo, tabaquismo, cirrosis, hemocromatosis,...). Si bien en la literatura no hay unanimidad respecto a la asociacion del consumo de AH con el CHC, algunos autores ya contemplaron esa posibilidad, excluyendo tambien otras etiologias reconocidas de CHC, por lo que deberia reevaluarse si su asociacion es aleatoria o por el contrario existe nexo causal. EnglishWe present a case of a middle-aged patient with sustained intake of hormonal contraceptives (AH) which develops multiple hepatic adenomas (well documented association) and hepatocellular carcinoma (HCC) unifocal giant without finding other risk factors for it (alcoholism, smoking, cirrhosis, hemochromatosis,...). While there is no unanimity regarding the association of consumption of AH with CHC in the literature, some authors already contemplated this possibility, also excluding other recognized etiologies of HCC, so you should assess whether your association is random or else there is a causal link.

Hepatocarcinoma gigante unifocal en mujer con ingesta prolongada de anticonceptivos hormonales: ¿casualidad o causalidad?