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In recent decade the number of organ, including kidney, transplantations both from dead and living donor has noticeably increased. Kidney transplantation is the gold standard of treatment of the patients at thermal chronic renal insufficiency stage [2]. In view of increasing numbers of patients with transplanted kidney, it is a compelling task to protect kidney transplant from chronic damage (rejection) and thereby improve remote post-transplantation results by way of changing the paradigm of post-transplantation immune suppression (IS) [2, 3].

Change of the pattern of management of the kidney transplant patients with terminal stage of chronic renal failure