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Bowen’s disease (BD) is a neoplastic skin disease and is also known as squamous cell carcinoma in situ of the skin. Etiological factors include irradiation, carcinogens, immunosuppression, and viruses. A 50-year-old man presented with persistent, progressive, slightly raised, red, and crusted plaque-like masses that occurred suddenly on both hands. A wide excision and local advancement flap were used for the masses. Atypical squamous cells proliferated through the entire thickness of the epidermis that was diagnosed as BD. This patient had been working with construction materials and was in the printing business. He also had a history of constant hand exposure to substances such as arsenic and tar; thus, it was possible that they contributed to this occurrence of BD. No sign of recurrence was detected at the 6 months follow-up. Therefore, early diagnosis and management are particularly important.

Bowen’s Disease on Both Hands Caused by Constant Exposure to Chemical Agents