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Background: Treatment of hypercholesterolemia often lasts a lifetime, therefore patients leave chemical drugs and choose herbal medicines. The aim of this clinical study is to evaluate the efficacy of antihiperkolesterol jamu formula consists of Guazuma ulmifolia leaves, Cassia senna leaves, Sonchus arvensis leaves, Camellia sinensis leaves, Curcuma xanthorrhiza rhizomes, Curcuma longa rhizomes and Phyllanthus niruri herbs to lowering cholesterol plasma level as part of Saintifikasi Jamu program. Methods: This study was a quasi-experimental with pre and post test design. The total subjects were 50 patients with mild hypercholesterolemia who met the inclusion criteria. The research took place at RRJ ‘Hortus Medicus’ Tawangmangu between September to December 2014. The data were analyzed using a paired t-test with SPSS 16 software. Results: Results showed jamu anticholesterol formula which is taken every day for 28 days lowered the mean of cholesterol plasma level of 212.42 mg / dl to 196.6 mg / dl. Paired t test at 95% confidence level acquired p value <0.05, showed that there is significant differences in the mean cholesterol level subjects before and after the study. Conclusion: The administration of jamu antihypercholesterol formula for 28 days could reduce plasma cholesterol level in subjects with mild hypercholesterolemia. (Health Science Journal of Indonesia 2018;9(2):87-92)

Jamu formula could reduce plasma cholesterol patients with mild Hypercholesterolemia