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Bu calismada, Artemisia campestris (L) bitkisi etanol ekstraktinin yavru gokkusagi alabaliklarinda gorulen Spironucleosis (Hexamitiasis) enfeksiyonlari uzerine in vivo antiparazitik aktivitesinin belirlenmesi amaclanmistir. Ortalama agirliklari 1,5-2,0 g olan enfekte gokkusagi alabaliklarina, 1,0, 1,5, 2,0 2,5 ve 3,0 g/kg oranlarinda bitki ekstrakti ilaveli yemlerle 7 gun ve 21 gun periyotlarda tedavi uygulamasi yapilmistir. A. campestris (L) etanol ekstraktinin GC-MS ile analizlenmesi sonucunda major bilesenleri; acenaphthylene 1,2– dihydro (%62,70), n-octadecane (%4,66), capillin (%4,95), curcumene (%4,45), 2.4-pentadiynylbenzene (%7,28), benzaldehyde (%2,53), methacrolein (%1,35) olarak tespit edilmistir. Tedavi uygulamasi sonunda elde edilen sonuclara gore, deney gruplarinda ve pozitif kontrol grubunda kumulatif mortalitenin negatif kontrol grubuna gore azaldigi gorulmustur (p<0,05). Enfeksiyonun yogunlugu ve orani uzerine 21 gunluk tedavi uygulamasinin 7 gunluk uygulamadan daha etkili oldugu belirlenmistir. Arastirma sonuclarimizda, A. campestris (L) ekstraktinin gokkusagi alabaliklarinda Spironucleus salmonis’e karsi antiparazitik etki sagladigi belirlenmistir. Anahtar kelimeler Artemisia campestris(L), Spironucleus salmonis, Oncorhynchus mykiss, antiparaziter, tedavi.

Use of Artemisia campestris (L) on Treatment of Spironucleosis Infection in Rainbow Trout (Oncorhynchus mykiss)