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Objective: To evaluate the relative humidity and temperature over the cornea in three different eye glass frame designs to see if frame design can influence relative humidity and temperature measured over the eyeball surface. Setting: Ophthalmology practice in the Denver, Colorado area Design: Prospective study Materials and Methods: Relative humidity and temperature were measured in 59 subjects in a clinical setting, with three different eye glass frame designs from June 2016 to September 2016. Measurements were made with small sensors mounted inside the eye glass lenses, to see if eyeglass frame design could influence these measured values. Baseline measures were taken with glasses off and follow-up measures with glasses on. Results: Relative humidity increased most markedly with a tight wraparound frame design (38.9%), followed by a smaller increase with post cataract wraparound sunglass frames (2.8%), and a minimal decrease with normal frames (-1.3 %).  The temperature increased over the eyeball in all frame designs, but changed most dramatically in the tight wraparound frame (11.2 degrees). Conclusion: Tight wraparound eyeglass frames significantly increase the relative humidity over the cornea, as measured in this study. This frame design may offer another method of treatment for dry eye disease that is lower in cost than present therapies. Key Words: Dry Eye Disease, Relative Humidity.

Effects of Three Eye Glass Frame Designs on Relative Humidity and Temperature Measured Over the Cornea