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In a 4-week experiment, growing rats were fed diets containing 30% transgenic potatoes with overexpression of P14-3-3 protein, non-transgenic dehydrated potato tubers of the same variety (Desiree), or a control diet. The activity of dehydroepiandrosterone (DHEA) as well as increases in the concentrations of NO3 ions, Fe and Zn in the liver of rats fed diets containing transgenic potatoes were observed. The reaction might be related to oxidative stress linked to the altered chemical composition of potato tubers resulting from transgenesis, changed concentrations of some minerals or biologically active substances.

Transgenic potato tubers with overexpression of 14-3-3 protein in growing rat diets. 1. Selected hormone activities and liver function status