English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Abstrak Acinetobacter baumannii merupakan spesies Acinetobacter spp. tersering diisolasi dari manusia, dan lebih sering dijumpai pada infeksi nosokomial dibandingkan dengan infeksi di komunitas. Eksistensi bakteri ini di lingkungan terkait dengan keragaman reservoir, kemampuan memperoleh gen pembawa sifat resisten antimikroba, dan sifat resisten terhadap pengeringan. Infeksi disebabkan strain A.baumannii yang resisten terhadap banyak antibiotik tidak mudah dikendalikan dan menjadi permasalahan di berbagai negara. Penelitian ini bertujuan untuk mengetahui prevalensi A.baumannii dari spesimen klinis di instalasi mikrobiologi klinik RSUP Haji Adam Malik serta pola kepekaannya terhadap berbagai antibiotik. Identifikasi dan uji kepekaan menggunakan mesin otomatis Vitek 2 dengan Advanced Expert System (AES). Penelitian ini menemukan 644/3693 (17,44%) isolat A.baumannii dari berbagai spesimen klinis. A.baumannii paling banyak diisolasi dari spesimen dahak. Penelitian ini menemukan 147/644 (23%) bahwa isolat carbapenem-resistent A.baumannii (imipenem dan meropenem). Sebagian besar isolat sensitif terhadap colistin, amikacin dan tigecycline. Prevalensi A.baumanni yang ditemukan pada penelitian ini adalah rendah namun resistensinya tinggi terhadap antibiotik terutama golongan penicillin, cephalosporin dan fluoroquinolon. Abstract Acinetobacter baumannii is the most frequent species of Acinetobacter spp. isolated from humans and more common in nosocomial infection than it is in community acquired infection. A.baumannii existence in environment is associated with the diversity of its reservoirs, its capacity to accumulate genes of antimicrobial resistence, and its resistence to desiccation. Infection of Multidrug resistent (MDR) strain of A.baumannii is not easy to manage and it has become a problem in many countries. The aim of this retrospective study was to investigate the prevalence of A.baumannii from routine clinical specimens sent to clinical microbiology laboratory RSUP HAM Medan and its susceptibility pattern to various antibiotics. Identification and susceptibility testing of A. baumannii was performed by Vitek 2 with Advanced Expert System (AES). A total of 644/3693 (17.44%) A.baumannii isolates were identified from various clinical specimens. From those isolates, there were 147 (23%) isolates of carbapenemresistent A.baumannii (imipenem and meropenem). A.baumannii mainly isolated from sputum specimens, and most isolates were highly sensitive to colistin, amikacin and tigecycline. Low prevalence of A.baumannii was found in this study. However, the isolates showed high resistence level to antibiotics, particularly penicillin, cephalosporin and fluoroquinolones.

PREVALENCE OF ACINETOBACTER BAUMANNII ISOLATED FROM CLINICAL SPECIMENS IN ADAM MALIK HOSPITAL