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B-decays mediated by both charged currents and neutral currents have provided hints of violation of lepton flavour universality. By assuming an explanation of these anomalies in terms of new physics at the TeV scale affecting the third fermion generation, we review the relevant constraints. In particular we illustrate the effects of electroweak radiative corrections and their impact on a consistent interpretation of the data. The simplest scenario is ruled out and we briefly discuss the modifications required to simultaneously describe the whole set of anomalies.

b-anomalies related to leptons and LFV: new directions in model building