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Background: Study the effect of drain on outcome of primary TKR. Method: Prospective study, 150 patients with primary TKR randomly divided into three groups, without drain: Group-A, Group-B: drain for 24 hours and Group-C: drain for 48 hours. With minimum follow-up period of 1 year. Functional outcome majored with KSS-Knee Society Score and VAS-Pain Visual Analogue Scale. Result: The decrease in haemoglobin in post-operative 3day was statistically significant between all the groups (p<0.05). The mean drop in haemoglobin is group-B was 1.84 gm% and 2.59 gm% in Group-C. Patients in group with no drain are having maximum post-operative pain scores among the all groups. The post-operative Knee Society Score in all postoperative follow up at 1 month, 3 months & 1 year, with the scores being lower in patients in whom drain was not kept. There is no significant difference in KSS & between two groups with drain at 1 and 3 months follow up, but there is significant difference in Knee Society Score in between these two groups at 1 year follow up (p=0.004). There are 7 patients in group-A who are having superficial infection post-operatively in comparison to 2 patients in group-A & 3 patients in Group-C. Conclusion: Post operatively significantly higher blood loss is associated with use of drain, not using a drain is associated with significantly  higher pain in immediate postoperative period and Use of drain for 48 hours postoperatively is associated with  significantly better outcome of total knee replacement

Study of the role of surgical drain on outcome of total knee replacement surgery