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Osteoporosis negatively affects the patients quality of life and results in high Healthcare cost. Teriparatide is a synthetic polypeptide hormone that contains 1-34 amino acid fragment of the recombinant human parathyroid hormone and it is claimed to fasten fracture healing. Hence we decided to carry out a study to find out the effect of teriparatide injection if given for short term, in elderly osteoporotic intertrochanteric fractures, in the postoperative period. Materials and Methods: We carried out non randomised, controlled non inferiority clinical trial at MIMER medical college talegaon dabhade from 1 august 2018 to 31 July 2019. We enrolled patients into two groups. Group A received injection teriparatide 20 microgram daily with 400 IU of Vitamin D3 and 1200 milligram calcium for 3 months in the post-operative period. Group B received only 400 IU of Vitamin D3 and 1200 milligram of calcium for 3 months. We followed up patients at 6 weeks, 12 weeks, 24 weeks, 36 weeks for pain at fracture site, radiological sign of union. Results: Results of our study showed that Union time in group A(patients who received teriparatide) was significantly less than group B. Harris hip score was also significantly better in group A as compared to group B. Conclusion: In this prospective, non randomised controlled, non-inferiority clinical trial 3 months of injection teriparatide after surgery was associated with significantly shorter time for fracture union, better functional outcome and no complications.

To study the role of short term teriparatide injection in the management of intertrochanteric fracture of hip in elderly patients after osteosynthesis