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The Non aqueous titration method was developed for quantitave analysis of LCarnitine L-Tartarate in multivitamin tablets. The Non aqueous titration method was carried out using 0.1 N Perchloric acids. The present analytical method was validated according to ICH guidelines (ICH,Q2(R1)). The calibration curve was found to linear with correlation coefficient (r 2=0.99995), Bias (-0.35) in the range of 50 to 150 % of standard solution. The precision and recovery were determined and all the parameter value found within acceptance limit. The value for both method and intermediate precision were found to 0.57 % and recovery found to 99.11 to 99.59 %. The validation parameter study was method precision, intermediate precision, Linearity and recovery. This is a convenient, precise and rapid accurate method for the estimation of L-Carnitine L-Tartarate in Bulk and Pharmaceutical dosage forms (Multivitamin Tablets).

journal of drug delivery and therapeutics

Analytical method development and validation of L-Carnitine L-Tartarate in Pharmaceutical Dosage forms (Multivitamin tablets) using non aqueous titration