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The recurrence of oral squamous cell carcinoma (OSCC) in compromised surgical border can be easily explained by the persistence of residual tumor. However, when the surgical borders are not compromised, the progression may be related to the presence of adjacent genetically modified cells generated by the primary tumor. The different methods used in the evaluation of surgical borders are not perfect and have limitations. In veterinary medicine, histological analysis by intraoperative frozen still has technical and economic restrictions limiting their use. Molecular studies demonstrate the potential contribution to a better prognosis through the characterization of a gene profile that allows a more accurate risk. This article reviews the methods of analysis of surgical borders, highlighting the importance of feline models to understand the molecular biology of human oral carcinoma.

Avaliação de margens cirúrgicas e recorrência local do carcinoma de célula escamosa oral de felino