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Retrospective, case-control study was conducted using data from the clinical records collected at a referral hospital between 2011 and 2018 where vaccination records were available. 27 dogs with a diagnosis of inflammatory central nervous system disease were ageand gender-matched with an equal number of control dogs presented in the same time period for other diseases. Dogs who were vaccinated within 28 days before the onset of clinical signs of immune-mediated central nervous system disease were considered as a positive case in this study. To assess the association between recent vaccination and the onset of disease, odds ratio were calculated and categorical data was analysed using Fisher’s exact test.

Preliminary findings of an investigation into the association between vaccination and immune-mediated diseases of the canine central nervous system