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Client-owned cats ≥1 year of age, weighing ≥2 kg, with a documented loss (≥5%) in body weight (BW) were included. Cats were treated once daily with either 2 mg/ cat mirtazapine transdermal ointment (Kindred Biosciences, Inc.) or placebo ointment applied to the inner surface of the pinna for 14 ± 3 days. Mean percent change in BW between the mirtazapine and placebo group was evaluated from Day 1-to-14. A post-hoc analysis was conducted to evaluate the subset of enrolled cats with suspected renal disease (defined as having urine specific gravity <1.035 and serum creatinine >122 μmol/L [1.6 mg/ dL] at baseline).

Renaltec attenuates serum levels of indoxyl sulfate in geriatric cats