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Cyanopyridine derivatives shows good biological and therapeutic activities and exhibit wide range of applications in the field of pharmaceutical and agriculture. Cyanopyridine derivatives like some new N-(4-(6-Amino-5-cyano-4-aryl-pyridin-2yl)phenyl)cyclopropane carboxamide of type (2a-l) have been prepared by the condensation of such new chalcone derivatives N(4-(3-Arylacryloyl)phenyl)cyclopropane carboxamide of type (1a-l) with Malononitrile in presence of Ammonium acetate. All the prepared compounds were characterized by their spectral (I.R., 1H NMR. & Mass) data and screened for their antimicrobial activities.

Synthesis and Biological Screening of N-(4-(6-Amino-5-cyano-4-aryl-pyridin-2-yl) phenyl) cyclopropane Carboxamide