English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Submandibular gland of Suncus murinus (suncus) was examined by light and electron microscopy, and the level of nerve growth factor (NGF) (from 10 to 380 postnatal days) was measured by bioassay. Granular convoluted tubules (GCT) were well-developed in male and less in female animals after 20 postnatal days when NGF activity of glandular extracts reached the adult level. GCT cells contained secretory granules of heterologous size and electron opacity, and large membrane bodies consisted of concentrically arranged cisterns. Secretory acini were composed of serous and mucous type of cells and myoepithelium. NGF activity in the suncus submandibular gland rapidly increased after 14 postnatal days and reached plateau in 20 postnatal days. NGF activity in suncus prostate also increased after 30 postnatal days and reached plateau in 45 postnatal days. The total NGF activity in the adult male submandibular gland was l4-times higher than that in the adult female. NGF activity of extract of submandibular gland was measured by bioassay and enzyme immunoassay to know cross-reactivity ofNGF of these species with mouse NGF. Cross-reactivity of suncus NGF with mouse NGF is much lower than that of guinea-pig and rabbit NGF. It is suggested that suncus NGF much differs in molecular homology from mouse, guinea-pig and rabbit NGF. Recently we discovered asource rich in nerve the one hand, and molecular properties of growth factor (NGF, (20)) in the submandibular gland of the house musk shrew Suncus murinus (Insectivora: Soricidae) and a weak NGF activity in the prostate of this animal (21). Potent sources of NGF in mammals had previously been restricted to submandibular gland or prostate of some species in rodents (submandibular gland: mouse (5), Praomys natalensis (1), prostate: guinea pig (7)) and lagomorphs (prostate: rabbit, (8)). Our finding poses interesting questions on the relationship between morphological features and the presence of NGF in submandibular gland on NGF on the other. In the present study, we tried to define morphological characteristics of the suncus submandibular gland in comparison with mouse submandibular gland, and also compared biological and immunological properties ofNGF in the shrew, mouse, guinea pig and rabbit. The results show that the histological and ultrastructural features of the submandibular gland in the shrew are rather unique among mammals, and molecular properties ofNGF differ from those in rodents and lagomorphs.

biomedical research

&lt;b&gt;NERVE GROWTH FACTOR AND THE SUBMANDIBULAR GLAND OF THE HOUSE MUSK SHREW&lt;i&gt; SUNCUS MURINUS&lt;/i&gt;: A MORPHOLOGICAL AND COMPARATIVE IMMUNOLOGICAL &lt;/b&gt;&lt;b&gt;STUDY &lt;/b&gt;