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We investigated the lipopolysaccharide (LPS) from Penner's serotype 19 (PEN 19) of C. jejuni that had been isolated from a patient with the Guillain-Barre syndrome (GBS). The LPS was extracted from the bacterium and separated by a silica beads column chromatography. One homogeneous fraction showing reactivity with the patient's serum, rabbit anti-G M1 antibody, and also with cholera toxin, which binds oligosaccharide of G M1 , was obtained

biomedical research

&lt;b&gt;Cross-reactive antigen between nervous tissue and a bacterium elicits Guillain-Barré syndrome: Molecular mimicry between ganglioside G&lt;sub&gt;M1&lt;/sub&gt;, and lipopolysaccharide from Penner’s serotype 19 of &lt;i&gt;Campylobacter &lt;/i&gt;&lt;/b&gt;&lt;b&gt;&lt;i&gt;jejuni &lt;/i&gt;&lt;/b&gt;