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The authors report a novel approach for enhancing the oral absorption of paclitaxel (PTX) by encapsulation in poly(anhydride) nanoparticles (NPs) containing cyclodextrins and poly(ethylene glycol).

Pharmacokinetics and Antitumor Efficacy of Paclitaxel–Cyclodextrin Complexes Loaded in Mucus-Penetrating Nanoparticles for Oral Administration