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The distribution and impact of aerosol-delivered gold nanoparticles (AuNPs) functionalized with a mixture of aminated-polyvinyl alcohol and amino-PEG ([polyvinyl alcohol/PEG]-NH 2 ) upon repeated administration onto a 3D lung model were explored.

Distribution of polymer-coated gold nanoparticles in a 3D lung model and indication of apoptosis after repeated exposure