English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Objectives: The aim of this research was to see the effect of Lawsonia inermis (Linn.) leaves ethanolic extract (LLEE) on liver histopathological of alloxan-induced Wistar rats. Methods: Thirty-five of male Wistar rats grouped into five groups, i.e., K (normal) given 0.9% NaCl solution and P1–P4 were induced using alloxan (120 mg/kg BW) intraperitoneally. P2–P4 was given LLEE, i.e., 200 mg/kg BW, 400 mg/kg BW, and 600 mg/kg BW for 28 days. On 29th day, all Wistar rats of the group were sacrificed to take its liver. Histology preparation of liver by paraffin slicing method of hematoxylin-eosin staining. The observation was done under a microscope with ×40 and ×100 magnification. Observation of the liver histopathological includes changes of the central venous, sinusoid, hepatocyte morphology, and glycogen accumulation, P1–P4 compared to K. Result: The results showed that in P4 group, LLEE dose 600 mg/Kg BW for 28 days able to improve liver tissues structure of alloxan-induced Wistar rats. Conclusion: The LLEE at dose 600 mg/Kg BW effective can restore the liver destruction of alloxan-induced Wistar rats.

HISTOPATHOLOGICAL LIVER TISSUES OF ALLOXAN-INDUCED WISTAR RATS THAT GIVEN LAWSONIA INERMIS (LINN.) LEAVES’ ETHANOLIC EXTRACT