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Objective: This study aimed to compare the effect of Curcuma xanthrorrhiza ethanol extract to the viability of Streptococcus mutans and  Aggregatibacter   actinomycetemcomitans using single- and dual-species biofilm at different phases of formation. Methods: Biofilm models were incubated for 4, 12, and 24 hrs, then exposed to the extract at a concentration of 0.525%. Results: The viability of the single-species S. mutans biofilm was low (p 0.05) was found between singlespecies A.  actinomycetemcomitans  and dual-species biofilm. Conclusions: Curcuma xanthorrhiza ethanol extract is more effective for decreasing the viability of single-species S. mutans biofilm.

asian journal of pharmaceutical and clinical research

THE EFFECT OF CURCUMA XANTHORRHIZA ETHANOL EXTRACT ON THE VIABILITY OF STREPTOCOCCUS MUTANS AND AGGREGATIBACTER ACTINOMYCETEMCOMITANS (DENTAL BIOFILM RESEARCH: IN VITRO STUDY)