Open AccessFibroblast Growth Factor 23 and the Last Mile
Author(s) -
Orlando M. Gutiérrez
Publication year - 2020
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.13631119
Subject(s) - fibroblast growth factor 23 , medicine , fgf21 , excretion , fibroblast growth factor , fibroblast , urinary system , endocrinology , phosphorus , growth hormone , hormone , parathyroid hormone , biochemistry , calcium , biology , in vitro , chemistry , receptor , organic chemistry
Fibroblast growth factor 23 (FGF23) is a bone-derived hormone that regulates phosphorus balance by enhancing urinary phosphorus excretion and inhibiting the synthesis of 1,25-dihydroxyvitamin D [1,25(OH)2D] ([1][1]). Its discovery and characterization could be considered a triumph for precision
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