Open AccessEndogenous Testosterone, Endothelial Dysfunction, and Cardiovascular Events in Men with Nondialysis Chronic Kidney Disease
Author(s) -
Mahmut İlker Yılmaz,
Alper Sönmez,
Abdul Rashid Qureshi,
Mutlu Sağlam,
Peter Stenvinkel,
Halıl Yaman,
Tayfun Eyıleten,
Kayser Çağlar,
Yusuf Oğuz,
Abdullah Taşlıpınar,
Abdülgaffar Vural,
Mahmut Gök,
Hilmi Umut Ünal,
Müjdat Yenicesu,
Juan Jesús Carrero
Publication year - 2011
Publication title -
clinical journal of the american society of nephrology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.755
H-Index - 151
eISSN - 1555-905X
pISSN - 1555-9041
DOI - 10.2215/cjn.10681210
Subject(s) - medicine , testosterone (patch) , kidney disease , renal function , dialysis , diabetes mellitus , endocrinology , proportional hazards model , endothelial dysfunction , type 2 diabetes , hemodialysis
Deterioration of kidney function impairs testosterone production, with hypogonadism being common in men with chronic kidney disease (CKD). In nonrenal populations, testosterone is suggested to participate in the atherosclerotic process. In male dialysis patients, we showed that low testosterone increases the risk of mortality. We here studied plausible links among testosterone levels, vascular derangements, and cardiovascular events in nondialysis CKD men.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom